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The decreased macrophages (clusters 2, 4, 5, 7) suggested that FAPCAR-T cells disrupted the viscous inflammatory-fibrosis cycle via the clearance of overactivated fibroblasts, which was consistent with the flow cytometry and proteomics results

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After a normalization procedure with ProgenesisQI, which we also previously described, we determined ions estimated to have derived from the eye drop-delivered drugs, as well as the metabolites of these drugs and their additives (Supplementary Table 1)