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Sleep-Wake Regulation: Vitamin B12 contributes to the regulation of the bodys internal clock and circadian rhythm

Common symptoms can include: Extreme fatigue Lethargy Loss of appetite headaches Feeling faint or dizzy Breathlessness Headaches Heart palpitations Tinnitus Additional symptoms of B12 deficiency can include psychological problems such as low mood, irritability, depression, cognitive changes, or blurred memory

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doi: 10.1038/cdd.2014.135 73 TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells

Patients see an improvement in quality of life measures in 6 months such as having more energy, improved libido, and increase in strength