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Description

OATP transporters expressed on the sinusoidal membrane of the hepatocytes play an important role in hepatic uptake of many endogenous and exogenous conjugates

Imai and Nakagawa, 2003

Such a redox imbalance, apparently, leads to an increase in the amount of oxidized forms of low-molecular-weight thiols in cells and, as a result, to a depression (decrease in efficiency) of protective mechanisms involving thiols