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End products of this reaction are reduced glutathione and NADP + (Figure 2)

Furthermore, peripheral estrogen hydroxylation was found to be increased in both men and women with SLE and estrogenic metabolites were reported to increase B cell differentiation and activate T cells [44]

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TB-500 is dosed less frequently, typically once or twice per week during a loading phase and once every two weeks during maintenance, reflecting its longer half-life and systemic distribution pattern