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Metabolomics to predict acute kidney injury in cirrhosis

The hematin-dihydroartemisinin adduct mobilizes a potent mechanism to suppress -hematin crystallization

SLC7A11, a key ferroptosis regulator, is a transmembrane protein that is part of the system Xc, responsible for cystine import into cells for cysteine synthesis and GSH production (79,80)

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In the absence of antioxidants or other inhibitors, LOO can abstract a hydrogen from another lipid molecule (LH), producing another highly reactive carbon centered radical (L ), which then propagates the radical chain as presented in Figure 2 (Waldeck and Stocke, 1996)