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Herein, we did not identify studies that correlated effort-related motivational aspects, such as those assessed by the Effort-Based Decision-Making and Learned Helplessness tests, in animal models of anxiety or depression subjected to exposure to caffeine and related xanthines, while also evaluating inflammatory parameters

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Shibao C, Arzubiaga C, Roberts LJ, Raj S, Black B, Harris P, Biaggioni I

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