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Conclusively, Dox-associated myocardial cells demise may have been at least partially prevented by Bcl-2 upregulation, along with a concomitant decrease of Bax expression

Common endpoints studied: Body weight change Nitrogen retention / protein synthesis Tissuespecific response Metabolic readouts (contextdependent) Dosing Protocol (Research context) Research Protocol (InVivo) Most Citable Structures A) Continuous infusion model (7 days): 0.9 mg/kg/day des(13) IGF1 7 days (osmotic minipump)

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doi: 10.3389/fnagi.2016.00308 59 WangPCuiYRenQYanBZhaoYYuPet al