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Some of these compounds can chelate free radicals and augment transcription machinery by Nrf2 and ROS, thereby depriving them of the ability to induce oxidative stress, a condition that is associated with neuronal pathology

Brain : J Neurol

3.4 Iron While iron deficiency (ID) has long been recognized as a driver of ineffective erythropoiesis in CKD, emerging evidence highlights that both iron deficiency and iron overload disrupt RBC longevity by promoting eryptosisthe programmed, non-hemolytic death of mature erythrocytes characterized by PS externalization, cell shrinkage, and cytoskeletal rearrangement (Lang K

An herb with phytonutrients is referred to as a adaptogen if it helps the body adapt by (a) restoring system functions to normal, (b) building resistance to future stress, and (c) raising the bodys functioning to a higher level of performance [3]

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