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Varkaris A, Katsiampoura A, Davis JS, Shah N, Lam M, Frias RL, Ivan C, Shimizu M, Morris J, Menter D, Overman M, Tran H, Heymach J, Chun YS, Vauthey JN, Calin G, Kopetz S

Importantly, mTORC1 activity also varies depending on the duration of starvation: it is repressed during acute starvation, whereas prolonged nutrient deprivation leads to robust reactivation of mTORC1

Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis

Comprehensive investigations should also explore EGCGs therapeutic potential across diverse demographic groups, considering age, genetic variations, and distinct neurological disease progression patterns

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Pharmacy (Basel)