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Med Gas Res 8(1):1923 Park JS, Chyun JH, Kim YK, Line LL, Chew BP (2010) Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans

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The reduced expression of GR in limbic regions, associated with FKBP51 dysregulation and hormonal variations of the female reproductive cycle, favors the establishment of a state of resistance to glucocorticoids, resulting in prolonged exposure to glucocorticoids and low-grade inflammation, which supports the higher prevalence and vulnerability of women to the development and maintenance of MDD (Palumbo et al., 2020

Amer J Med Gen

Glutathione is classified as generally safe for long-term use

In DOX-treated cells and mouse hearts, levels of NLRP3 and related proteins were elevated, and calycosin (CA) ameliorated cardiotoxicity via the NLRP3 pathway (99)