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Ripay, a plant pathogen effector protein, exhibits robust -glutamyl cyclotransferase activity when stimulated by eukaryotic thioredoxins

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Aliev et al., 2020)

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It also helps in reversing the imbalance of matrix metalloproteinases (MMP-9) and their inhibitors (TIMP-1), and in preventing epithelial-mesenchymal transition (EMT) through the modulation of Nrf2, NF-B, and TGF-1/Smad2/3 signaling pathways 6