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This mechanism explains accelerated healing across multiple tissue types including bone

It could also make the scar worse

So it was having like a beneficial effect on inflammation as well

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High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks

CYP7A1 is simultaneously inhibited by an FXR-small heterodimer partner (SHP), which is the downstream target of FXR in the liver, whereas FXR in enterocytes inhibits CYP7A1 activation in hepatocytes by secreting fibroblast growth factor 19 (FGF19) and binding to fibroblast growth factor receptor 4 (FGFR4) on the hepatocyte membrane (77)