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doi: 10.1016/j.metabol.2021.154886 118 SkjaerbaekCFrystykJOrskovHKissmeyer-NielsenPJensenMBLaurbergSet al

Additionally, they found a significant reduction in GPX4 and xCT proteins in mice treated with Con A

23 Furthermore, although these criteria recognize CADM as a DM subtype, there are only three skin manifestations (Gottrons sign, Gottron papules, and heliotrope rash) included in the scoring assessments, and patients without all three may not meet the scoring threshold for probable CADM/IIM

Secondly, EGT can interact with other natural antioxidant defense systems in the body, such as activating the intracellular antioxidant pathway involving MAPKs and regulating the levels of peroxidases and antioxidant enzymes like superoxide dismutases (Kawano et al., 1983