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While large-scale clinical trials in human subjects remain an area of ongoing investigation, the preclinical data consistently demonstrates positive effects on follicular cell activity

Wegrowski Y, Maquart F, Borel J

Additionally, studies show that in acute psychological stress, GABA levels are decreased by 18% in the prefrontal cortex.[ref] Studies also show that patients diagnosed with major depressive disorder have lower levels of GABA in the cortex than healthy controls

Lipoic acid might be able to increase glutathione synthesis in aged rats by up-regulating the expression of -glutamylcysteine ligase (-GCL), the rate-limiting enzyme in glutathione synthesis (31), and by increasing cellular uptake of cysteine, an amino acid required for glutathione synthesis (32)

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Cancer 89:14401447 Smith PS, Zhao WL, Robbins ME (2007) Inhibiting catalase activity sensitizes 36B10 rat glioma cells to oxidative stress