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Source: Xu et al., Nature (2025)

In 12% of the subjects, grade 3 neurotoxicity was observed only for cumulative oxaliplatin doses equal or above 1110 mg/m 2

Interestingly, GAMT activity was not detected in the head kidneys or proximal intestine in all groups of Phase-II HSB

These authors administered increasing doses of calcitriol to rats either at the time of inducing chronic kidney failure or at a later time point, when uremia was already well established

Expert Opin Drug Metab Toxicol 12:14791490

Cook, Botulinum toxin type a inhibits calcitonin gene-related peptide release from isolated rat bladder, Journal of Urology, vol