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Intriguingly, a significant increase in total and selenium-dependent GPx ratios was observed ( P = 0.0099 and P = 0.0096, respectively) (Figures 6D and E), indicating an adaptive upregulation to mitigate oxidative damage, while the non-selenium-dependent GPx ratio remained stable (Figure 6F)

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here, control cells were treated using the same volume of DMSO

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Moreover, vitamin B2 intake was found to be significantly, negatively and linearly correlated with odds of osteoporosis, and positively and linearly associated with BMD in regions of total femur, trochanter and intertrochanter, while positively and nonlinearly associated with femoral BMD