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Chronic insomnia often involves multiple dysfunctions within sleep-wake pathways, neurotransmitter circuits, glial regulation, and circadian rhythm coordination

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A 15 l aliquot of proteinCIPp-18 mixture containing 8% sucrose was loaded into separate wells on the agarose gel and electrophoresis was carried out at 200 V/cm for ~ 35 min in running buffer (25 mM TrisHCl, pH 7.4)

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women comprised 67.6%, and most had dyslipidemia or hypertension at baseline

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