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Rapid coordinated motions such as swimming and feeding in primitive metazoans, for example, would require that cellular contractions are synchronized

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While in 21monthold VEGFA hyper mice ERG amplitudes (a and bwaves) for both darkadapted and lightadapted conditions were severely diminished (consistent with the severe RPE and photoreceptor degeneration observed by histologic analysis), targeting caspase1/caspase11 or Il1r1 in VEGFA hyper mice partially normalized ERG amplitudes (Fig 10AC)