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Thiol Oxidation Normal physiological functions and cellular metabolism are finely regulated by the cellular redox status, which is continuously exposed to a dynamic fluctuation (41)

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This was confirmed by the use of the natural agonist of mGluR1 (glutamate) which was correlated with an increase in cell viability in melanoma cells but failed to stimulate phosphoinositide (PI) hydrolysis, indicating that the activation of mGluR1 did not follow the canonical PLC/PI signaling in melanoma

Nature 426 , 787 (2003)

This may involve shared regulators of ferroptosis and autophagy, such as mTOR and p38MAPK

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