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doi: 10.1038/nrneph.2017.107 90 ZuoZJingKWuHWangSYeLLiZet al

Ferroptosis: a central player in ARDS pathogenesis Ferroptosis is a regulated, iron-dependent form of cell death distinguished by oxidative damage and lipid peroxidation

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Long term ALG-000184 dosing has been well tolerated with no serious adverse events (AEs) reported and no subjects requiring discontinuation of study drug