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447 Zhou et al

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Autoimmun Rev 14(2):174180 Banga JP, Schott M (2018) Autoimmune thyroid diseases

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used asiatic acid to treat RA-FLSs and reported that increasing concentrations of asiatic acid significantly increased the expression of the Nrf2/HO-1 protein and inhibited downstream NF-B signalling, which in turn increased the expression of proapoptotic proteins (Bax and caspase-3) and decreased the expression level of the antiapoptotic protein Bcl-2, increasing the level of apoptosis and inhibiting the proliferation and cloning of RA-FLSs

Generally speaking, elective surgery requires a two-to-four week recovery time of rest and slow reintegration into your normal activities