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The tumor stroma elevates the expression of proteases such as plasminogen activation system and matriptase that are involved in the activation of pro-HGF

It does this by helping blood vessels form

It was first developed in 1991 as a derivative of Body Protection Compound, a peptide naturally found in human gastric juices [1, 2]

This extended period of efficacy stems from Dihexa's ability to modulate the expression levels of synapse-associated proteins (such as PSD-95, GluA1, etc.), rather than simply stimulating neuronal electrical activity

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