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14,15 As the understanding of -cell biology advances, a combination of stem cell therapy and gene editing presents promising prospects for diabetes treatment, although further evaluation is needed to determine long-term efficacy and safety

This process is facilitated by lysosomal iron release and its uptake into mitochondria, resulting in the induction of the mitochondrial permeability transition and ultimately hepatocyte necrosis

doi: 10.1038/ncomms7734 99 IrapordaCErreaARomaninDECayetDPereyraEPignataroOet al

nIpamorelin is a pentapeptide (5-amino acid) GHRP that selectively binds ghrelin receptors on somatotroph cells to trigger GH release

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Loss of DPEP1 markedly relieved FA- or cisplatin-induced AKI by altering the apoptosis and ferroptosis, but not the pyroptosis or necroptosis