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Microbial-derived metabolites induce actin cytoskeletal rearrangement and protect blood-brain barrier function

Biochem Biophys Res Commun 289:8084 Lushchak VI (2012) Glutathione homeostasis and functions: potential targets for medical interventions

Journal of Food Science 84 (6): 16091620

Interestingly, 45% of MASLD patients with PNPLA3 GG allele were also FADS2 TT allele-positive, and MASLD patients with the combination had a higher ratio of advanced fibrosis than PNPLA3 GG allele alone-positive patients (70% and 17%, p=0.027)

Increased GH and IGF-1 may indirectly modulate gonadotropins and sex steroids to support ovulation and spermatogenesis, so track LH, FSH, testosterone, estrogen, progesterone, and SHBG to assess response