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4 TCM metabolites and their role in modulating the PI3K/Akt pathway in UC treatment As one of the treasures of traditional Chinese culture, TCM stands out with its unique diagnostic and therapeutic methods and proven clinical efficacy

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This suggests that the gut macrobiotic and its metabolites are engaged in the progression of atherosclerosis, and also that dysbiosis of gut flora is linked with systemic inflammation (Drosos et al., 2015)