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However, it is not clear whether the diversity of astrocytes may have an impact on the way different brain regions age, and particularly the hippocampus, a region involved in the mechanisms of learning and memory

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Disruption of a RAC1-centred network is associated with Alzheimers disease pathology and causes age-dependent neurodegeneration

In insulin-resistant states, RET is facilitated by impaired OXPHOS, and is particularly prominent during conditions of re-oxygenation or metabolic stress

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