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Reports that neurotoxic aldehydes, which are normally rapidly metabolized by aldehyde dehydrogenase in the brain, accumulate in parkinsonian substantia nigra because aldehyde dehydrogenase gene expression is significantly reduced

Proper refrigerated storage: Store in main refrigerator section (not freezer) Keep away from freezer compartment (avoid freezing) Don't store in door (temperature fluctuates) Protect from light (keep in box or wrap in foil) Label with reconstitution date Signs of degradation: Cloudiness or particles (should be clear) Color change (should remain same color as when mixed) Unusual odor Loss of effectiveness If you notice any of these, discard and prepare fresh solution

[DOI] [PubMed] [Google Scholar] 43.Concha J.S.S., Werth V.P