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The search was limited to articles published in English, with a focus on recent studies (20102024) while including seminal older works for historical context

Unlike typical hemolytic anemias, fragmentation anemias can be (and frequently are) non-regenerative as cytokines associated with the primary disease concurrently suppress the bone marrow

1, 22, 23, 24, 25 In a recent study, researchers suggested that taking oral birth control pills increased oxidative stress (free radicals) and that supplementing with antioxidants Vitamin C and Vitamin E increased the activity of naturally occurring antioxidant glutathione and reduced levels of free radicals

44 Proteins such as transferrin and caeruloplasmin chelate metals (iron and copper, respectively), preventing free radical formation