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Additionally, lipoic acid increased mitochondrial biogenesis through triggering AMP-activated protein kinase (AMPK)-induced transcription factor PGC-1 activation in skeletal muscle of aged mice (48)

Subsequent study has shown the same mechanism in hepatocellular carcinoma (HCC)

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doi: 10.1136/jnnp.74.1.44 35 BorghammerPChakravartyMJonsdottirKYSatoNMatsudaHItoKet al

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