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Vitamin B12, also called cobalamin, is essential for red blood cell formation, nerve health, DNA production, and energy metabolism

Homocysteine and cardiovascular disease Observational studies indicate that even moderately elevated blood concentrations of homocysteine raise the risk of cardiovascular disease (CVD), although randomized controlled trials of homocysteine-lowering therapy have generally not translated to reductions in adverse cardiovascular outcomes (26, 27)

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As a person ages, the level of homocysteine in the blood increases, leading to the development of dementia