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Upon HGF binding c-MET gets activated through kinase activity which is followed by receptor dimerization and trans-phosphorylation of two catalytic tyrosine residues Tyr1234 and Tyr1235 within the kinase activation region [31]

krlec, K., Ruman, R., Jarc, E., Sikiri, P., vajger, U., Petan, T., Perii Nanut, M., trukelj, B., & Berlec, A

doi:10.1016/j.snb.2015.06.072 17

Built for the increasing complexity of CNS clinical development, the latest release enhances precision, scales image data processing, and strengthens data quality oversight across global trials