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The role of ferroptosis in human diseases Proteintech Group Ferroptosis: Opportunities and Challenges in Cancer Ferroptosis: Death by Lipid Peroxidation: Trends in Cell Biology Ferroptosis at the crossroads of cancer acquired drug resistance and immune evasion Nature Reviews Cancer The role of glutathione peroxidase 4 in neuronal ferroptosis and its therapeutic potential in ischemic and hemorrhagic stroke ScienceDirect Mechanism of ferroptosis, glutathione peroxidase 4 (GPX4) glutathione Download Scientific Diagram

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Under low-iron conditions, IRPs bind to IREs in the untranslated regions (UTRs) of target mRNAs, stabilizing TfR1 and DMT1 transcripts while suppressing translation of ferritin and FPN1

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