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We review emerging metabolism-based interventions used in psychiatry, including pharmacologic agents (metformin, glucagon-like peptide-1 agonists and pioglitazone), lifestyle strategies (intermittent fasting, ketogenic metabolic therapy and exercise) and theoretical models (mitochondrial dysfunction, allostatic load model and selfish brain hypothesis)

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Despite these promising findings, the current body of evidence remains limited by heterogeneous study designs, small sample sizes, insufficient standardization of herbal formulations, and a lack of robust immune-related biomarkers

On the other hand, people who have prosthetics, like crowns, bridges or veneers, that match the color of and are located very close to their natural teeth should not whiten them

Although the reason is not yet known, AD has a gender-specific epidemiologic profile, with women disproportionately affected in both prevalence and severity 60,61

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