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Expert Opin Drug Metab Toxicol 5:10231038 Nicholson JK, Lindon JC, Holmes E (1999) Metabonomics: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

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A preclinical meta-analysis focusing on diabetic peripheral neuropathy models confirmed that EV-based therapy improved neurovascular remodeling without detectable toxicity

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[66] [67] [68] It is worth noting that ATP, an end product of glycolysis, is also a substrate of phosphofructokinase-1