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Practical stacking considerations Researchers interested in replicating a CagriSema-like protocol need to manage two separate peptides with their own reconstitution, storage, and dosing requirements

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We can prepare a homogeneous saturated solution by adding excess solute (in this case, greater than 35.9 g of NaCl) to the solvent (water), stirring until the maximum possible amount of solute has dissolved, and then removing undissolved solute by filtration

doi: 10.1038/s41401-024-01228-5 38 LinkermannASkoutaRHimmerkusNMulaySRDewitzCDe ZenFet al

J Am Chem Soc 144:72837294 Shima H, Tsurita G, Wada S, Hirohashi Y, Yasui H, Hayashi H, Miyakoshi T, Watanabe K, Murai A et al (2019) Randomized phase II trial of survivin 2B peptide vaccination for patients with HLA-A24-positive pancreatic adenocarcinoma

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