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Does BST-1, a protein homologous to CD38, play a role in organismal NAD homeostasis

The difference in results between local and non-local administration remains unclear from available research

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3.3 DARA treatment lowers ADO and elevates INO to concentrations within the receptor-activating range in MM patients To determine whether the in vitro findings translate to the clinical setting, we next quantified ADO and INO levels in paired BM and PB samples collected from 7 MM patients treated with DARA monotherapy ( Table 1 )