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CrAT deficiency leads to accumulating acetyl-CoA, which exerts an allosteric inhibiting effect on pyruvate dehydrogenase (PDH), a rate-limiting enzyme for pyruvate entry into the Krebs cycle

G., and Brunelli, S

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Uboveja A, Huang Z, Buj R, Amalric A, Wang H, Tangudu NK et al

What was also statistically significant was the benefit of L-carnitine supplementation for specific subgroups of subjects

As these variants were all recorded in the clinical notes of each patient by the Corresponding Author, obviously this post-analysis was biased in terms of the plausibility of disease relationship based upon preconceived concepts of CVS pathophysiology in the literature and by that clinician