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NCOR1 deficiency triggers lipid synthesis in hepatocytes by increasing FASN and acetyl-CoA carboxylase (ACC) expression

Kuessel L, Wenzl R, Proestling K, Balendran S, Pateisky P, Yotova 1st, et al

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Full normalization is more likely when underlying contributors like excess body fat, poor sleep, inflammatory diets, and chronic stress are addressed alongside treatment