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For the purposes of this comparison, the important point is narrow and factual: tesamorelin and sermorelin are both GHRH-receptor agonists, so they share a mechanism with each other and with native GHRH, but not with the ghrelin-receptor secretagogues

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It binds to melanocortin receptors (primarily MC1R) and stimulates melanogenesis the production of melanin in the skin

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