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Description

At this level, the central nervous system is severely suppressed, and vital functions like breathing and heart rate slow to life-threatening levels

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Psychiatry 57 , 10681072 (2005)

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However, full effects are noticed within six months of treatment

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These defects were attenuated by treatment with the pharmacologic GCase activator NCGC758 213 , indicating that rescue of GCase activity could have therapeutic benefits in preventing aberrant inflammation

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DOI: 10.1016/s0378-8741(00)00195-1 83

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Heterozygous mutants were further discriminated from wild type (+/+) animals using microsatellite marker analysis

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