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In addition to neural connections, the central clock system also synchronizes the circadian rhythms of the peripheral clock system through hormones or factors, such as arginine vasopressin (AVP) and tumor necrosis factor (TNF) ( FIGURE 1 The clock system mainly regulates metabolism in the following three ways

Within the mucus, there is a wide range of mucus-degrading bacteria: Bacteroides thetaiotaomicron, Akkermansia muciniphila, Bacteroides fragilis, Bifidobacterium bifidium, and Ruminoccous gnavus

Without estrogen, fat tends to accumulate around the abdomen

Este aumento de la actividad de los fibroblastos produce un aumento significativo en la produccin de colgeno y elastina, vitales para la cicatrizacin de heridas y la regeneracin cutnea