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Furthermore, more recently, it has been observed that the accumulation of DHA in N2a and HN33.11 neuronal cells, generated under conditions of cellular stress due to intracellular oxidation of AA, induces non-apoptotic neuronal death, called necroptosis ( 6

The interaction is purely pharmacodynamic (how the peptides function in the body), not pharmacokinetic (how the peptides are absorbed or degraded)

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Blood 84(10):305a, 1994

We finally performed stratified analysis, finding that LPD to be especially beneficial in terms of high metabolomic response for PSC patients with UC (but not PSC patients with CD, or PSC alone), which is consistent with the clinical response