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In a randomised controlled clinical trial, administration of a recombinant canarypox virus expressing feline IL-2 was well tolerated and resulted in a significantly longer median time to relapse and a significant reduction in the risk of relapse at one year and two years (Jas et al., 2015)

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The mechanism is slow because it works by reprogramming fat cells, not by suppressing appetite

And, clearly, there are shortcomings to the current drug-approval process

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Apart from microRNAs, another well-known family of tiny non-coding RNAs is P-element-induced wimpy testis piRNAs