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Postmortem analyses have confirmed astrocyte activation in the substantia nigra of PD patients, accompanied by elevated pro-inflammatory cytokines [tumor necrosis factor- (TNF-), IL-1, transforming growth factor-, and IL-6], ROS, NO, pro-apoptotic proteins, and T-cell infiltration

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Biochemical Profile: TB4 (Thymosin Beta-4) The second active constituent operating within this complex matrix is TB4, the full-length 43-amino acid sequence of the naturally occurring protein, Thymosin Beta-4