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Its main biological function is the transport of acyl CoA residues to the mitochondrial matrix in a process called the carnitine cycle

In addition, NRF2 can also regulate the transcriptional expression of metabolites involved in intermediate metabolism, some of which play essential roles in the regeneration of NADPH, a key electron donor needed to reduce oxidative substrates [108]

He also assessed patients for their fibromyalgia-like score

10.1016/S0002-9440(10)63847-3

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An appropriate ROS concentration is conducive to normal angiogenesis and vascular homeostasis, while a high concentration of ROS chronically induces ferroptosis and consequently causes pathological damage to blood vessels