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This is its central mechanism of action

Mller J, Sidler D, Nachbur U, Wastling J, Brunner T, Hemphill A

doi: 10.1104/pp.108.1.47 18 de LucasM.DavireJ

However, the realization that diverse regulatory pathways often converge, motivated a number of studies that eventually demonstrated the importance of GH, IGF-I, and IGF-IR in many processes of immune function [156]