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Anemia due to blood loss the primary focus of this guide is subdivided by acuity: Acute posthemorrhagic anemia (D62) : Anemia resulting from sudden, significant blood loss (e.g., trauma, surgical hemorrhage, GI bleeding event, ruptured aneurysm)

PRDXs act as cellular antioxidants and may relay H 2 O 2 signaling, with PRDX I and II targeted by HDAC6, decreasing H 2 O 2 reductive activity