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In total, there is strong support for targeting TRIMs in an effort to develop effective therapies for a wide-array of cancers

Systems biology offers a powerful framework to understand the multi-cellular and cross-organ interactions between lung and brain microenvironments that drive asthma pathogenesis

The sprout extract of Tuscan black cabbage, a type of kale, was found to be protective against a high-fat diet in rats, restoring antioxidant and phase II enzyme levels and lowering serum lipids (total cholesterol, triacylglycerides, non-esterified fatty acids) (Melega et al., 2013)

Although particular antioxidant compounds express extraordinary antioxidant capacity in vitro , more challengeable and complex in vivo studies, which will perfectly simulate an intracellular environment with the presence of an orchestrated network of pro and antioxidants should be conducted

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Notably, studies have shown that upon stimulation with butyrate, CD8 + T cells exhibit increased sensitivity to IL-15, leading to the expression of higher levels of the transcription factor FoxO1 [98] (Fig