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Results Identification of GPX4 Allosteric Activator In the previous study, we have identified a potential allosteric site in the crystal structure of human GPX4 U46C mutant (hGPX4-C, PDB entry 2OBI

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Eur Heart J 33:531537 Prinz M, Jung S, Priller J (2019) Microglia biology: one century of evolving concepts

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More than a century ago, the groundbreaking work of Otto Warburg revealed that tumor cells preferentially metabolize glucose to lactate via the glycolytic pathway even under oxygen-sufficient conditions, rather than engaging in efficient mitochondrial oxidative phosphorylation

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