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doi: 10.3389/fpsyt.2025.1589663 Received 10 March 2025 Accepted 06 May 2025 Published 29 May 2025 Volume 16 - 2025 Edited by Paulo Santos, University of Porto, Portugal Reviewed by Martn Garca Juarez, Autonomous University of Nuevo Len, Mexico Gayane Vardanyan, Yerevan State Medical University, Armenia Updates Copyright 2025 Luan, Wang, Shi, Zhang, Wang, Zhou, Wu, Liu, Li, Zhang, Shao, Chen, Chu and Wei

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Therefore, it is reasonable using supplementation of liposomal glutathione, instead of the N-acetylcysteine or bonded cysteine utilized as precursors for GSH cell synthesis, since patients with deficient levels of glutamate-cysteine ligase and GSH synthetase will not be able to use N-acetylcysteine or bonded cysteine as substrates to synthesize their own GSH

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